Endocrine Abstracts

Case History: A 61 year old woman on haemodialysis with end stage renal failure secondary to immune-complex mediated diffuse proliferative glomerulonephritis was admitted with accelerated hypertension presenting with acute right microvascular 6th nerve palsy and left optic nerve ischaemic atrophy. Her BP had been well controlled over the last 10 years but since the end of 2020 systolic BP readings were frequently recorded above 200mmHg. Multiple antihypertensive classes were c...

Introduction: Accurate preoperative localisation in primary hyperparathyroidism enables a localised approach to a parathyroidectomy operation. Ultrasonography is the most commonly used first-line imaging modality due to its widespread availability and safety. Parathyroid scintigraphy using MIBI is commonly used as the second-line imaging modality, as recommended by NICE. 4D-CT may have a role as a third-line imaging modality, when ultrasound and scintigraphy do not clearly loc...

Case history: A 30-year-old Ugandan male, now living in UK, presented to A&E with confusion and agitation. Capillary blood glucose was 0.9 mmol/l and he was commenced on intravenous Dextrose. During blood donor screening in Uganda, he was told that he had a blood-borne infection. He had gross hepatomegaly on examination. During admission, he experienced repeated episodes of hypoglycaemia despite increased dietary intake of carbohydrates and continuous infusions of 5%-10% D...

Introduction: 99m/Tc-MIBI parathyroid scintigraphy (MIBI) is the most common test used for pre-operative localization of parathyroid adenoma in primary hyperparathyroidism. We evaluated the influence of serum calcium and parathyroid hormone (PTH) levels on sensitivity of MIBI imaging in successful parathyroid localisation in patients identified as having primary hyperparathyroidism.Methods and material: Retrospective review of 403 patients who had MIBI s...

Intravenous Immunoglobin (IVIG) therapy is used in recurrent miscarriage, despite its efficacy being limited to specific sub-groups such as those with underlying immune conditions. The indications, efficacy and side effect profile of IVIG when used in pregnant women are not established. We present the case of a 41-year-old pregnant woman with one previous miscarriage, who had received IVIG as part of her fertility treatment and subsequently developed profound symptoms and bioc...